Technology
DURAMESH™ - The World's First and Only Suturable Mesh
Suturable Mesh combines the desirable principles of a mesh repair with the placement precision of a suture
Technology
DURAMESH™ - The World's First and Only Suturable Mesh
Suturable Mesh combines the desirable principles of a mesh repair with the placement precision of a suture
The Problem
Sutures can cut through otherwise intact tissue due to the presence of a sharp leading edge - described as "suture pull-through" or "cheese-wiring" - leading to repair failure.
Meshes better distribute forces to limit tissue tearing, but they introduce their own complications, such as chronic pain, adhesions, fistulas, migration, and infection.
A device is needed that both distributes forces without introducing mesh-related complications.
Suture Pull-Through Can Cut Intact Tissue
Sutures can cut through otherwise intact tissue due to the presence of a sharp leading edge - described as "suture pull-through" or "cheese-wiring" - leading to repair failure.
Meshes distribute forces and allow for tissue ingrowth.
The Best of Both Worlds
Duramesh™ combines the desirable principles of a mesh repair with the placement precision of a suture.
A Best of Both Worlds Solution - Suturable Mesh
Suturable Mesh combines the desirable principles of a mesh repair with the placement precision of a suture. It is the world's only device that both approximates tissue and permits ingrowth for a stronger, earlier repair.3
It is the world's only device that both approximates tissue and permits ingrowth for a strong early repair.3
Innovative Design to Distribute Forces
Duramesh™ has more surface area to distribute forces.1
Innovative Design to Distribute Forces
Duramesh's patented design has more surface area than standard sutures to distribute forces and reduce suture pull-through.1 Unlike standard sutures, Duramesh flattens to better distribute forces at the suture-tissue interface.2
Duramesh™ flattens to better distribute forces at the suture-tissue interface.2
Allows Tissue Incorporation2
Duramesh™ has an open-walled, hollow core design to allow tissue incorporation of the device during healing.
Allows Tissue Incorporation2
Duramesh's filaments flatten parallel to the incision, and its open-walled, hollow core design allows tissue incorporation into the device during healing.
DURAMESH™'s Dynamic Diameter
Duramesh™'s diameter decreases with axial tension so that it can be passed through tissue easily.
Duramesh's Dynamic Diameter
Duramesh's diameter decreases with axial tension so that it can be passed through tissue easily.
Easy to Handle, Use, and Tie
Duramesh™'s handling and use are similar to those of a standard suture.
Duramesh™'s novel design allows it to collapse when tied, resulting in a low-profile knot as compared to its outsized diameter. In knot size and knot strength testing, Duramesh™ knots were shown to be stronger than standard suture knots for the same number of throws.
Duramesh™ requires at least 4 alternating throws for a secure, low-profile knot.
A Stronger, Earlier Repair3
Repairs with Duramesh revealed less gap formation and more intact repairs in comparison to conventional sutures in an in-vivo rabbit tendon model. Duramesh repairs were twice as strong as standard suture at two weeks.
A Strong Early Repair3
Duramesh™ minimizes gap formation and allows for tissue ingrowth and implant incorporation.
1. Experimental Study of the Characteristics of a Novel Mesh Suture
G A Dumanian, A Tulaimat, Z P Dumanian, Experimental study of the characteristics of a novel mesh suture, British Journal of Surgery, Volume 102, Issue 10, September 2015, Pages 1285–1292, https://doi.org/10.1002/bjs.9853
2. Suturable Mesh Demonstrates Improved Outcomes over Standard Suture in Porcine Laparotomy Closure Model
Dumanian GA. Suturable Mesh Demonstrates Improved Outcomes over Standard Suture in a Porcine Laparotomy Closure Model. Plast Reconstr Surg Glob Open. 2021 Oct 15;9(10):e3879. doi: 10.1097/GOX.0000000000003879. PMID: 34667699; PMCID: PMC8519206.
3. An In Vivo Comparison: Novel Mesh Suture Versus Traditional Suture-Based Repair in a Rabbit Tendon Model
Janes LE, Mioton LM, Fracol ME, Ko JH. An In Vivo Comparison: Novel Mesh Suture Versus Traditional Suture-Based Repair in a Rabbit Tendon Model. J Hand Surg Glob Online. 2021 Nov 19;4(1):32-39. doi: 10.1016/j.jhsg.2021.10.003. PMID: 35415598; PMCID: PMC8991626.
Sutures Can Cut Intact Tissue
Sutures can cut through otherwise intact tissue due to the presence of a sharp leading edge - described as "suture pull-through" or "cheese-wiring" - leading to repair failure.
Meshes distribute forces and allow for tissue ingrowth.
The Problem
Sutures can cut through otherwise intact tissue due to the presence of a sharp leading edge - described as "suture pull-through" or "cheese-wiring" leading to repair failure.
Meshes better distribute forces to limit tissue tearing, but they introduce their own complications, such as chronic pain, adhesions, fistulas, migration, and infection.
A Best of Both Worlds Solution - Suturable Mesh
Suturable Mesh combines the desirable principles of a mesh repair with the placement precision of a suture.
The Best of Both Worlds
Duramesh™ combines the desirable principles of a mesh repair with the placement precision of a suture. It is the world's first device that both approximates tissue and allows ingrowth for a strong early repair.3
It is the world's only device that both approximates tissue and permits ingrowth for a stronger, earlier repair.3
Innovative Design to Distribute Forces
Duramesh's patented design has more surface area than standard sutures to distribute forces and reduce suture pull-through.1
Innovative Design to Distribute Forces
Duramesh™ has more surface area to distribute forces.1 Duramesh™ flattens to better distribute forces at the suture-tissue interface.2
Allows Tissue Incorporation2
Duramesh's filaments flatten parallel to the incision, and its open-walled, hollow core design allows tissue incorporation into the device during healing.
Allows Tissue Incorporation2
Duramesh™ has an open-walled, hollow core design to allow tissue incorporation of the device during healing.
Duramesh's Dynamic Diameter
Duramesh's diameter decreases with axial tension so that it can be passed through tissue easily.
DURAMESH™'s Dynamic Diameter
Duramesh™'s diameter decreases with axial tension so that it can be passed through tissue easily.
Easy to Handle, Use, and Tie
Duramesh™'s handling and use are similar to those of a standard suture.
Duramesh™'s novel design allows it to collapse when tied, resulting in a low-profile knot as compared to its outsized diameter. In knot size and knot strength testing, Duramesh™ knots were shown to be stronger than standard suture knots for the same number of throws.
Duramesh™ requires at least 4 alternating throws for a secure, low-profile knot.
A Strong Early Repair3
Duramesh™ minimizes gap formation and allows for tissue ingrowth and implant incorporation.
A Stronger, Earlier Repair3
Repairs with Duramesh revealed less gap formation and more intact repairs in comparison to conventional sutures in an in-vivo rabbit tendon model. Duramesh repairs were twice as strong as standard suture at two weeks.
References
1. Experimental Study of the Characteristics of a Novel Mesh Suture
G A Dumanian, A Tulaimat, Z P Dumanian, Experimental study of the characteristics of a novel mesh suture, British Journal of Surgery, Volume 102, Issue 10, September 2015, Pages 1285–1292, https://doi.org/10.1002/bjs.9853
2. Suturable Mesh Demonstrates Improved Outcomes over Standard Suture in Porcine Laparotomy Closure Model
Dumanian GA. Suturable Mesh Demonstrates Improved Outcomes over Standard Suture in a Porcine Laparotomy Closure Model. Plast Reconstr Surg Glob Open. 2021 Oct 15;9(10):e3879. doi: 10.1097/GOX.0000000000003879. PMID: 34667699; PMCID: PMC8519206.
3. An In Vivo Comparison: Novel Mesh Suture Versus Traditional Suture-Based Repair in a Rabbit Tendon Model
Janes LE, Mioton LM, Fracol ME, Ko JH. An In Vivo Comparison: Novel Mesh Suture Versus Traditional Suture-Based Repair in a Rabbit Tendon Model. J Hand Surg Glob Online. 2021 Nov 19;4(1):32-39. doi: 10.1016/j.jhsg.2021.10.003. PMID: 35415598; PMCID: PMC8991626.